Reflection Properties of the Human Skin From 40 to 110 GHz: A Confirmation Study (Bioelectromagnetics)

Andreas Christ, Adrian Aeschbacher, Fereshteh Rouholahnejad, Theodoros Samaras, Bernadetta Tarigan, and Niels Kuster, Bioelectromagnetics, Volume 42, No. 7, pp. 562 – 574, October 2021, online 21 July 2021; doi: 10.1002/bem.22362

Feasibility of Temperature Control by Electrical Impedance Tomography in Hyperthermia (Cancers)

Redi Poni, Esra Neufeld, Myles Capstick, Stephan Bodis, Theodoros Samaras, and Niels Kuster, Cancers, Volume 13, Issue 13, Article No. 3297, online 30 June 2021; doi: 10.3390/cancers13133297

The SPARC DRC: Building a Resource for the Autonomic Nervous System Community (Front. physiol.)

Mahyar Osanlouy, Anita Bandrowski, Bernard De Bono, David Brooks, Antonino M. Cassarà, Richard Christie, Nazanin Ebrahimi, Tom Gillespie, Jeffrey S. Grethe, Leonardo A. Guercio, Maci Heal, Mabelle Lin, Niels Kuster, Maryann E. Martone, Esra Neufeld, David Phillip Nickerson, Elias G. Soltani, Susan J. Tappan, Joost B. Wagenaar, Katie Zhuang, and Peter Hunter, Frontiers in Physiology 2021, Volume 12, 929, online 24 June 2021; https://doi.org/10.3389/fphys.2021.693735

Compliance Assessment of the Epithelial or Absorbed Power Density Below 10 GHz Using SAR Measurement Systems (Bioelectromagnetics)

Theodoros Samaras, Andreas Christ, and Niels Kuster, Bioelectromagnetics, September 2021, Volume 42, Issue 6, Pages 484–490, online 15 June 2021; https://doi.org/10.1002/bem.22355

In Silico Voltage-Sensitive Dye Imaging Reveals the Emergent Dynamics of Cortical Populations (Nat. Commun.)

Taylor H. Newton, Michael W. Reimann, Marwan Abdellah, Grigori Chevtchenko, Eilif B. Muller, and Henry Markram , Nature Communications 2021, Volume 12, 3630, online 15 June 2021; doi: https://doi.org/10.1038/s41467-021-23901-7

Radiofrequency-Induced Heating of Broken and Abandoned Implant Leads During Magnetic Resonance Examinations (Magn. Reson. Med.)

Aiping Yao, Tolga Goren, Theodoros Samaras, Niels Kuster, and Wolfgang Kainz, Magnetic Resonance in Medicine, October 2021, Volume 86, Issue 4, Pages 2156–2164, online 03 June 2021; doi: 10.1002/mrm.28836

FDA Extends MDDT Qualification to IMAnalytics V3.0 and MRIxViP V2.1

FDA Qualification of the IT’IS & ZMT MDDT toolset IMAnalytics with MRIxViP1.5T/3.0T and BCLib now also includes passive implants (ASTM F2182-19^ε2) and Region-of-Interest Field Extraction for ISO 10974 Tier 2.

The Impact of CT Image Parameters and Skull Heterogeneity Modeling on the Accuracy of Transcranial Focused Ultrasound Simulations (J. Neural Eng.)

Hazael Montanaro, Cristina Pasquinelli, Hyunjoo J. Lee, Hyunggug Kim, Hartwig R. Siebner, Niels Kuster, Axel Thielscher, and Esra Neufeld, Journal of Neural Engineering 2021, Volume 18, Issue 4, Article number: 046041, online 04 May 2021; doi: 10.1088/1741-2552/abf68d

Computational and Phantom-Based Feasibility Study of 3D dcNCI with Ultra-Low Field MRI (Front. Phys.)

Nora Höfner, Jan-Hendrik Storm, Peter Hömmen, Antonino M. Cassarà, and Rainer Körber, Frontiers in Physics 2021, Volume 9, Article number: 647376, online 26 April 2021; doi: 10.3389/fphy.2021.647376

IT'IS Annual Report 2020

Experimental and Numerical Optimization Modelling to Reduce Radiofrequency-Induced Risks of Magnetic Resonance Examinations on Leaded Implants (Appl. Math. Model)

Juan Córcoles, Aiping Yao, and Niels Kuster, Applied Mathematical Modelling, August 2021, Volume 96, pages 177–188, online 09 March 2021; doi: 10.1016/j.apm.2021.02.036

MRI Mice V1.0: New Mouse Models for Computational Investigations

IT’IS has released four new mouse models segmented from magnetic resonance imaging data. All four models – a pregnant model, a 12-week-old female and male model and a 3-week-old male model – are posable and are made available together with the corresponding MR images.

Radio-Frequency Electromagnetic Field Exposure and Contribution of Sources in the General Population: An Organ-Specific Integrative Exposure Assessment

Luuk van Wel, Ilaria Liorni, Anke Huss, Arno Thielens, Joe Wiart, Wout Joseph, Martin Röösli, Milena Foerster, Amelie Massardier-Pilonchery, Myles Capstick, Elisabeth Cardis, and Roel Vermeulen, Journal of Exposure Science & Environmental Epidemiology 2021, online 02 March 2021; doi: 10.1038/s41370-021-00287-8

Towards Blood Flow in the Virtual Human: Efficient Self-Coupling of HemeLB (Interface Focus)

J. W. S. McCullough, R. A. Richardson, A. Patronis, R. Halver, R. Marshall, M. Ruefenacht, B. J. N. Wylie, T. Odaker, M. Wiedemann, B. Lloyd, E. Neufeld, G. Sutmann, A. Skjellum, D. Kranzlmüller, and P. V. Coveney, Interface Focus, February 2021, Volume 11, 20190119, online 11 December 2020, doi: https://doi.org/10.1098/rsfs.2019.0122

NeuroRat V4-0 – Detailed Rat Anatomy for Neuromodulation Investigations

It’s a rat! After two long years of unremitting work, IT’IS has released NeuroRat V4-0, the first computational anatomical model with nerve trajectories for neuro-electrophysiology simulations. The new posable and functionalized whole-body model includes 179 tissues and functionalized nerve trajectories.

A Calibrated Physical Flow Standard for Medical Perfusion Imaging (Flow.Meas.Instrum)

Gertjan Kok, Nikola Pelevic, Amedeo Chiribiri, Xenios Milidonis, Muhummad Nazir, Myles Capstick, Sita Drost, Christian Poelma, Tobias Schaeffter, Flow Measurement and Instrumentation, April 2021, Volume 78, Article number: 101907, online 02 February 2021; doi: 10.1016/j.flowmeasinst.2021.101907

Restoration of Breathing after Opioid Overdose and Spinal Cord Injury Using Temporal Interference Stimulation (Commun. Biol.)

Michael D. Sunshine, Antonino M. Cassarà, Esra Neufeld, Nir Grossman, Thomas H. Mareci, Kevin J. Otto, Edward S. Boyden, and David D. Fuller, Communications Biology 2021, Volume 4, Article number 107, online 25 January 2021; doi: https://doi.org/10.1038/s42003-020-01604-x

MARTIN V1.0 and ViP Hand Library for WPT Evaluations

As of this week, a new whole body pediatric numerical simulation model of a 29-month-old boy is available in our extended Virtual Population (ViP) library. MARTIN V1.0 was developed by the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital, Boston, USA, and will be hosted by IT’IS. We are also pleased to announce the release of the IT’IS ViP Hand Library specifically designed for evaluation of wireless power transfer systems. 

Non-Invasive Suppression of Essential Tremor Via Phase-Locked Disruption of its Temporal Coherence (Nat. Commun.)

Sebastian R. Schreglmann, David Wang, Robert L. Peach, Junheng Li, Xu Zhang, Anna Latorre, Edward Rhodes, Emanuele Panella, Antonino M. Cassara, Edward S. Boyden, Mauricio Barahona, Sabato Santaniello, John Rothwell, Kailash P. Bhatia, and Nir Grossman, Nature Communications, January 2021, Volume 12, Article number: 363, online 13 January 2021; doi: 10.1038/s41467-020-20581-7

IT'IS Annual Report 2019

The annual report of the IT'IS Foundation for 2019 has been published and includes:  An overview of projects  How Z43 expands into new quarters: Moving to the Frontline! 

as well as information on:

Key figures and infrastructure Selected publications Our team, including the board members Selected guests, partners, and sponsors

Transmission Coefficient of Power Density into Skin Tissue Between 6 And 300 GHz (Radiat. Prot. Dosim.)

Andreas Christ, Theodoros Samaras, Esra Neufeld, and Niels Kuster, Radiation Protection Dosimetry, Volume 192, Issue 1, pages 113-118, online 4 December 2020; doi: 10.1093/rpd/ncaa179

Radiofrequency Electromagnetic Fields from Mobile Communication: Description of Modeled Dose in Brain Regions and the Body in European Children and Adolescents (Environ Res)

Laura Ellen Birks, Luuk Van Wel, Ilaria Liorni, Livia Pierotti, Mònica Guxens, Anke Huss, Milena Foerster, Myles Capstick, Marloes Eeftens, Hanan El Marroun, Marisa Estarlich, Mara Gallastegi, Llúcia González Safont, Wout Joseph, Loreto Santa-Marina, Arno Thielens, Maties Torrent, Tanja Vrijkotte, Joe Wiart, Martin Röösli, Elisabeth Cardis, Roel Vermeulen, and Martine Vrijheid, Environmental Research, Volume 193, February 2021, 110505, online 24 November 2020; doi: 10.1016/j.envres.2020.110505

Association between estimated whole-brain radiofrequency electromagnetic fields dose and cognitive function in preadolescents and adolescents

Alba Cabré-Riera, Luuk van Wel, Ilaria Liorni, Arno Thielens, Laura Ellen Birks, Livia Pierotti, Wout Joseph, Llucia Gonzalez, Jesús Ibarluzea, Amparo Ferrero, Anke Huss, Joe Wiart, Loreto Santa-Marina, Maties Torrent, Tanja Vrijkotte, Myles Capstick, Roel Vermeulen, Martine Vrijheid, Elisabeth Cardis, Martin Röösli, Mònica Guxens, International Journal of Hygiene and Environmental Health, February 2021, Volume 231, 113659, online 19 November 2020; doi: 10.1016/j.ijheh.2020.113659

Quantification of Clinically Applicable Stimulation Parameters for Precision Near-Organ Neuromodulation of Human Splenic Nerves (Commun. Biol.)

Isha Gupta, Antonino M. Cassara, Ilya Tarotin, Matteo Donega, Jason A. Miranda, David M. Sokal, Sebastien Ouchouche, Wesley Dopson, Paul Matteucci, Esra Neufeld, Matthew A. Schiefer, Alison Rowles, Paul McGill, Justin Perkins, Nikola Dolezalova, Kourosh Saeb-Parsy, Niels Kuster, Refet Firat Yazicioglu, Jason Witherington, and Daniel J. Chew, Communications Biology 2020, Volume 3, 577, online 16 October 2020; doi: 10.1038/s42003-020-01299-0

Theoretical Investigation on Broadband THz Deflectors for Femtosecond Electron Beam Diagnostics (Nucl. Instrum. Methods Phys. Res.)

Xiaoyu Liu, Micha Dehler, and Arya Fallahi, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Volume 986, Article Number: 164722, 11 January 2021, online 12 October 2020; doi: 10.1016/j.nima.2020.164722

Investigational Device for Temporal Interference Research

It’s been a challenge, but we made it: after several months of intensive work, we are excited to pre-announce our newly developed investigational stimulator prototype device for temporal interference brain research.

Evaluation of Specific Absorption Rate in the Far-Field, Near-to-Far Field and Near-Field Regions for Integrative Radiofrequency Exposure Assessment (Radiat. Prot. Dosim.)

Ilaria Liorni, Myles Capstick, Luuk van Wel, Joe Wiart, Wout Joseph, Elisabeth Cardis, Mònica Guxens, Roel Vermeulen, and Arno Thielens, Radiation Protection Dosimetry 2020, ncaa127, online 28 September 2020; doi: 10.1093/rpd/ncaa127

o²S²PARC Enters its Fourth Year

The o²S²PARC project continues to remain a priority at the IT’IS Foundation. The project focuses on building a comprehensive, freely accessible, intuitive, and interactive online platform to simulate peripheral nerve system neuromodulation and its impact on organ physiology in a precise and predictive manner.

Miss Able V3.0: The First-Ever Computational Monkey Model

IT’IS has released Miss Able V3.0, the first full-body monkey computational anatomical model. The new model features detailed nerve segmentations for all of the major peripheral nerves in the entire body and has more than 300 different individual tissue classes.

NeuHeart included in European Commission Innovation Radar

IT'IS is proud to be part of the NeuHeart project that has been selected to be included in the Innovation Radar of the European Commission.