MRI System Safety Evaluation



Simulations of induced MRI RF eddy current patterns in virtual human models.



Full EM simulations are applied to high-resolution anatomical models, in this case a pregnant woman.




Comparison of RF coil-induced SAR and corresponding temperature rise, considering thermoregulated and basal perfusion as well as thermal properties of tissues.

MRI System Safety Evaluation

Expertise and Infrastructure

The radio frequency (RF) and gradient coil fields from commercial scanners present a number of potential health risks for the patients. To develop the methodology for assessing MRI risks, IT'IS initiated the EUREKA Project MRI+, and several follow-up projects, with various partners from industry and academia. IT'IS performs customized evaluations of MRI exposure scenarios for a wide range of MR transmit technologies and patient populations. Based on the results, the critical parameters can be identified to improve overall patient safety. IT'IS has cooperated with major MRI manufacturers, including GE, Siemens and Philips, and actively contributes to the IEC 60601-2-33 safety requirements for medical MRI.

The group’s Yellow Submarine Laboratory is equipped with the most advanced tools including a PiX system, MITS-1.5T, -3T, -TT, -HFR, and -Gradient systems, the latest DASY8 RX90L with DASY52NEO licenses, and a wide range of specialized probes for E-field, SAR, H-field and voltage, including hardened probes designed specifically for MRI environments.  With more than 100 Sim4Life licenses, including the Virtual Population 3.x/4.x and multiple animal models, and several High Performance Computers (HPC) ranging from Graphics Processing Unit (GPU) clusters to supercomputers, our interdisciplinary research team can tackle highly specific and complex research tasks with superior innovation and efficiency – while ensuring compliance to national and international standards.


Select Customized Research Projects of the Past Years


Solutions Beyond State-of-the-Art

As new MRI technologies evolve, risk assessment becomes significantly more complex. As the current methods for demonstrating MR safety are still highly empirical, it is important to continue to protect higher-risk populations, such as patients with medical implants or impaired thermoregulation, without resorting to overly conservative risk estimates which stifle innovation and technological progress. The IT'IS Foundation is committed to expanding its MR safety activities collectively with potential partners.



We look forward to discussing with you how we can best support your R&D initiatives and regulatory submissions – simply call us at +41 44 245 96 96 or send us an email at



Brus, J., Heng, J.A., Beliaeva, V., Gonzalez Pinto, F., Cassarà, A.M., Neufeld, E., Grueschow, M., Imbach, L. & Polanía, R. Causal phase-dependent control of non-spatial attention in human prefrontal cortex. Nature Human Behaviour, 2024, doi:10.1038/s41562-024-01820-z
Bujard, C., Neufeld, E., Douglas, M., Wiart, J. & Kuster, N. A Gaussian process based approach for validation of multi-variable measurement systems: Application to SAR measurement systems. IEEE Access, 12:60404-60424, 2024, doi:10.1109/ACCESS.2024.3393778
Fasse, A., Newton, T., Liang, L., Agbor, U., Rowland, C., Kuster, N., Gaunt, R., Pirondini, E. & Neufeld, E. A novel CNN-based image segmentation pipeline for individualized feline spinal cord stimulation modeling. Journal of Neural Engineering, 21(3):036032, 2024, doi:10.1088/1741-2552/ad4e6b
Vassiliadis, P., Beanato, E., Popa, T., Windel, F., Morishita, T., Neufeld, E., Duque, J., Derosiere, G., Wessel, M.J. & Hummel, F.C. Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills. Nature Human Behaviour, 2024, doi:10.1038/s41562-024-01901-z
Boraschi, A., Spiegelberg, A., Karimi, F., Graf, K., Fallahi, A., Neufeld, E., Kuster, N. & Kurtcuoglu, V. The effect of body position change on noninvasively acquired intracranial pulse waves. Physiological Measurement, 44(3):035014, 2023, doi:10.1088/1361-6579/acc3d6
Karimi, F., Neufeld, E., Fallahi, A., Boraschi, A., Zwanenburg, J.J., Spiegelberg, A., Kurtcuoglu, V. & Kuster, N. Theory for a non-invasive diagnostic biomarker for craniospinal diseases. NeuroImage: Clinical, 37:103280, 2023, doi:10.1016/j.nicl.2022.103280
Missey, F., Ejneby, M.S., Ngom, I., Donahue, M.J., Trajlinek, J., Acerbo, E., Botzanowski, B., Cassarà, A.M., Neufeld, E., Glowacki, E.D., Shangold, L., Hanes, W.M. & Williamson, A. Obstructive sleep apnea improves with non-invasive hypoglossal nerve stimulation using temporal interference. Bioelectronic Medicine, 9(1):18, 2023, doi:10.1186/s42234-023-00120-7
Potok, W., Post, A., Beliaeva, V., Bächinger, M., Cassarà, A.M., Neufeld, E., Polania, R., Kiper, D. & Wenderoth, N. Modulation of visual contrast sensitivity with tRNS across the visual system, evidence from stimulation and simulation. eNeuro, pages ENEURO.0177—22.2023, 2023, doi:10.1523/ENEURO.0177-22.2023
Rintoul, J.L., Neufeld, E., Butler, C., Cleveland, R.O. & Grossman, N. Remote focused encoding and decoding of electric fields through acoustoelectric heterodyning. Communications Physics, 6(1):79, 2023, doi:10.1038/s42005-023-01198-w
Spiegelberg, A., Boraschi, A., Karimi, F., Capstick, M., Fallahi, A., Neufeld, E., Kuster, N. & Kurtcuoglu, V. Noninvasive monitoring of intracranial pulse waves. IEEE Transactions on Biomedical Engineering, 70(1):144-153, 2023, doi:10.1109/TBME.2022.3186748
Violante, I.R., Alania, K., Cassarà, A.M., Neufeld, E., Acerbo, E., Carron, R., Williamson, A., Kurtin, D.L., Rhodes, E., Hampshire, A., Kuster, N., Boyden, E.S., Pascual-Leone, A. & Grossman, N. Non-invasive temporal interference electrical stimulation of the human hippocampus. Nature Neuroscience, 26(2252):1994-2004, 2023, doi:10.1038/s41593-023-01517-y
Wessel, M.J., Beanato, E., Popa, T., Windel, F., Vassiliadis, P., Menoud, P., Beliaeva, V., Violante, I.R., Abderrahmane, H., Dzialecka, P., Park, C.H., Maceira-Elvira, P., Morishita, T., Cassarà, A.M., Steiner, M., Grossman, N., Neufeld, E. & Hummel, F.C. Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning. Nature Neuroscience, 26(2252):2005-2016, 2023, doi:10.1038/s41593-023-01457-7
Acerbo, E., Jegou, A., Luff, C., Dzialecka, P., Botzanowski, B., Missey, F., Ngom, I., Lagarde, S., Bartolomei, F., Cassarà, A.M., Neufeld, E., Jirsa, V., Carron, R., Grossman, N. & Williamson, A. Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers. Frontiers in Neuroscience, 16:945221, 2022, doi:10.3389/fnins.2022.945221
Aubry, J.F., Bates, O., Boehm, C., Butts Pauly, K., Christensen, D., Cueto, C., Gélat, P., Guasch, L., Jaros, J., Jing, Y., Jones, R., Li, N., Marty, P., Montanaro, H., Neufeld, E., Pichardo, S., Pinton, G., Pulkkinen, A., Stanziola, A., Thielscher, A., Treeby, B. & van 't Wout, E. Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models. The Journal of the Acoustical Society of America, 152(2):1003-1019, 2022, doi:10.1121/10.0013426
Botzanowski, B., Donahue, M.J., Ejneby, M.S., Gallina, A.L., Ngom, I., Missey, F., Acerbo, E., Byun, D., Carron, R., Cassarà, A.M., Neufeld, E., Jirsa, V., Olofsson, P.S., Głowacki, E.D. & Williamson, A. Noninvasive stimulation of peripheral nerves using temporally‐interfering electrical fields. Advanced Healthcare Materials, 11(17):2200075, 2022, doi:10.1002/adhm.202200075
Christ, A., Fallahi, A., Neufeld, E., Balzano, Q. & Kuster, N. Mechanism of capacitive coupling of proximal electromagnetic sources with biological bodies. Bioelectromagnetics, 43(7):404-412, 2022, doi:10.1002/bem.22422
Poni, R., Neufeld, E., Capstick, M.H., Bodis, S. & Kuster, N. Rapid SAR optimization for hyperthermic oncology: Combining multi-goal optimization and time-multiplexed steering for hotspot suppression. International Journal of Hyperthermia, 39(1):758-771, 2022, doi:10.1080/02656736.2022.2080284
Rowald, A., Komi, S., Demesmaeker, R., Baaklini, E., Hernandez-Charpak, S.D., Paoles, E., Montanaro, H., Cassarà, A.M., Becce, F., Lloyd, B., Newton, T., Ravier, J., Kinany, N., D´Ercole, M., Paley, A., Hankov, N., Varescon, C., McCracken, L., Vat, M., Caban, M., Watrin, A., Jacquet, C., Bole-Feysot, L., Harte, C., Lorach, H., Galvez, A., Tschopp, M., Herrmann, N., Wacker, M., Geernaert, L., Fodor, I., Radevich, V., Keybus, K.V.D., Eberle, G., Pralong, E., Roulet, M., Ledoux, J.B., Fornari, E., Mandija, S., Mattera, L., Martuzzi, R., Nazarian, B., Benkler, S., Callegari, S., Greiner, N., Fuhrer, B., Froeling, M., Buse, N., Denison, T., Buschman, R., Wende, C., Ganty, D., Bakker, J., Delattre, V., Lambert, H., Minassian, K., van den Berg, C.A.T., Kavounoudias, A., Micera, S., Ville, D.V.D., Barraud, Q., Kurt, E., Kuster, N., Neufeld, E., Capogrosso, M., Asboth, L., Wagner, F.B., Bloch, J. & Courtine, G. Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis. Nature Medicine, 28:260-271, 2022, doi:10.1038/s41591-021-01663-5
Lemaire, T., Vicari, E., Neufeld, E., Kuster, N. & Micera, S. MorphoSONIC: A morphologically structured intramembrane cavitation model reveals fiber-specific neuromodulation by ultrasound. iScience, 24(9):103085-103085, 2021, doi:10.1016/j.isci.2021.103085
McCullough, J.W.S., Richardson, R.A., Patronis, A., Halver, R., Marshall, R., Ruefenacht, M., Wylie, B.J.N., Odaker, T., Wiedemann, M., Lloyd, B., Neufeld, E., Sutmann, G., Skjellum, A., Kranzlmüller, D. & Coveney, P.V. Towards blood flow in the virtual human: Efficient self-coupling of HemeLB. Interface Focus, 11(1):20190119, 2021, doi:10.1098/rsfs.2019.0119
Montanaro, H., Pasquinelli, C., Lee, H.J., Kim, H., Siebner, H.R., Kuster, N., Thielscher, A. & Neufeld, E. The impact of CT image parameters and skull heterogeneity modeling on the accuracy of transcranial focused ultrasound simulations. Journal of Neural Engineering, 18(4):046041, 2021, doi:10.1088/1741-2552/abf68d
Osanlouy, M., Bandrowski, A., de Bono, B., Brooks, D., Cassarà, A.M., Christie, R., Ebrahimi, N., Gillespie, T., Grethe, J.S., Guercio, L.A., Heal, M., Lin, M., Kuster, N., Martone, M.E., Neufeld, E., Nickerson, D.P., Soltani, E.G., Tappan, S., Wagenaar, J.B., Zhuang, K. & Hunter, P.J. The SPARC DRC: Building a resource for the autonomic nervous system community. Frontiers in Physiology, 12:1-18, 2021, doi:10.3389/fphys.2021.693735
Paulides, M.M., Rodrigues, D.B., Bellizzi, G.G., Sumser, K., Curto, S., Neufeld, E., Montanaro, H., Kok, H.P. & Dobsicek Trefna, H. ESHO benchmarks for computational modeling and optimization in hyperthermia therapy. International Journal of Hyperthermia, 38(1):1425-1442, 2021, doi:10.1080/02656736.2021.1979254
Poni, R., Neufeld, E., Capstick, M., Bodis, S., Samaras, T. & Kuster, N. Feasibility of temperature control by electrical impedance tomography in hyperthermia. Cancers, 13(13):3297, 2021, doi:10.3390/cancers13133297
Sunshine, M.D., Cassarà, A.M., Neufeld, E., Grossman, N., Mareci, T.H., Otto, K.J., Boyden, E.S. & Fuller, D.D. Restoration of breathing after opioid overdose and spinal cord injury using temporal interference stimulation. Communications Biology, 4(1):107, Springer US, 2021, doi:10.1038/s42003-020-01604-x
Yao, A., Murbach, M., Goren, T., Zastrow, E., Kainz, W. & Kuster, N. Induced radiofrequency fields in patients undergoing MR examinations: Insights for risk assessment. Physics in Medicine & Biology, 66(18), 2021, doi:10.1088/1361-6560/ac212d
Kainz, W., Neufeld, E., Bolch, W.E., Graff, C.G., Kim, C.H., Kuster, N., Lloyd, B., Morrison, T., Segars, P., Yeom, Y.S., Zankl, M., Xu, X.G. & Tsui, B.M.W. Advances in computational human phantoms and their applications in biomedical engineering — A topical review. IEEE Transactions on Radiation and Plasma Medical Sciences, 3(1):1-23, IEEE, 2019, doi:10.1109/TRPMS.2018.2883437
Lemaire, T., Neufeld, E., Kuster, N. & Micera, S. Understanding ultrasound neuromodulation using a computationally efficient and interpretable model of intramembrane cavitation. Journal of Neural Engineering, 16(4):046007, IOP Publishing, 2019, doi:10.1088/1741-2552/ab1685
Neufeld, E. & Kuster, N. Response to professor Foster's comments. Health Physics, 117(1):70-71, 2019, doi:10.1097/HP.0000000000001091
Niederhäusern, N.v., Ducray, A., Zielinski, J., Murbach, M. & Mevissen, M. Effects of radiofrequency electromagnetic field exposure on neuronal differentiation and mitochondrial function in SH-SY5Y cells. Toxicology in Vitro, 61:104609, Elsevier, 2019, doi:10.1016/j.tiv.2019.104609
Pfeifer, S., Carrasco, E., Crespo-Valero, P., Neufeld, E., Kühn, S., Samaras, T., Christ, A., Capstick, M. & Kuster, N. Total field reconstruction in the near field using pseudo-vector E-field measurements. IEEE Transactions on Electromagnetic Compatibility, 61(2):476-486, 2019, doi:10.1109/TEMC.2018.2837897
Sumser, K., Neufeld, E., Verhaart, R.F., Fortunati, V., Gerda M. Verduijn, , Drizdal, T., Walsum, T.v., Veenland, J.F. & Paulides, M.M. Feasibility and relevance of discrete vasculature modeling in routine hyperthermia treatment planning. International Journal of Hyperthermia, 36(1):801-811, Taylor & Francis, 2019, doi:10.1080/02656736.2019.1641633
Yao, A., Zastrow, E., Cabot, E., Lloyd, B., Schneider, B., Kainz, W. & Kuster, N. Anatomical model uncertainty for RF safety evaluation of metallic implants under MRI exposure. Bioelectromagnetics, 40(7):458-471, 2019, doi:10.1002/bem.22206
Yao, A., Zastrow, E., Neufeld, E. & Kuster, N. Efficient and reliable assessment of the maximum local tissue temperature increase at the electrodes of medical implants under MRI exposure. Bioelectromagnetics, 40(6):422-433, 2019, doi:10.1002/bem.22208
Al-Serori, H., Ferk, F., Kundi, M., Bileck, A., Gerner, C., sík, M.M., Nersesyan, A., Waldherr, M., Murbach, M., Lah, T.T., Herold-Mende, C., Collins, A. & Knasmüller, S. Mobile phone specific electromagnetic fields induce transient DNA damage and nucleotide excision repair in serum-deprived human glioblastoma cells. PLoS ONE, 13(4):e0193677, 2018
Dressel, S., Gosselin, M.C., Capstick, M.H., Carrasco, E., Weyland, M.S., Scheidegger, S., Neufeld, E., Kuster, N., Bodis, S. & Rohrer Bley, C. Novel Hyperthermia Applicator System Allows Adaptive Treatment Planning: Preliminary Clinical Results in Tumour-Bearing Animals. Veterinary and Comparative Oncology, 16(2):202-213, 2018, doi:10.1111/vco.12340
Liorni, I., Neufeld, E., Kühn, S., Murbach, M., Zastrow, E., Kainz, W. & Kuster, N. Novel Mechanistic Model and Computational Approximation for Electromagnetic Safety Evaluations of Electrically Short Implants. Physics in Medicine & Biology, 63(22), 2018
Neufeld, E., Carrasco, E., Murbach, M., Balzano, Q., Christ, A. & Kuster, N. Theoretical and Numerical Assessment of Maximally Allowable Power-Density Averaging Area for Conservative Electromagnetic Exposure Assessment Above 6 GHz. Bioelectromagnetics, 39(8):617-630, 2018, doi:10.1002/bem.22147
Neufeld, E. & Kuster, N. Systematic Derivation of Safety Limits for Time Varying 5G Radiation Exposure Based on Analytical Models and Thermal Dose. Health Physics, 115(6):705-711, 2018, doi:10.1097/HP.0000000000000930
Neufeld, E., Lloyd, B., Kainz, W. & Kuster, N. Functionalized anatomical models for computational life sciences. Frontiers in Physiology, 9:1594, 2018, doi:10.3389/fphys.2018.01594
Pfeifer, S., Carrasco, E., Crespo-Valero, P., Neufeld, E., Kühn, S., Samaras, T., Capstick, M., Christ, A. & Kuster, N. Total Field Reconstruction in the Near-Field Using Pseudo- Vector E-Field Measurements. IEEE Transactions on Electromagnetic Compatibility, 61, 2018
Poljak, D., Cvetković, M., Bottauscio, O., Hirata, A., Lakso, I., Neufeld, E., Reboux, S., Warren, C., Giannopolous, A. & Costen, F. On the Use of Conformal Models and Methods in Dosimetry for Nonuniform Field Exposure. IEEE Transactions on Electromagnetic Compatibility, 60(2):328-337, 2018
Wagner, F.B., Mignardot, J.B., Le Goff-Mignardot, C.G., Demesmaeker, R., Komi, S., Capogrosso, M., Rowald, A., Seá\~nez, I., Caban, M., Pirondini, E., Vat, M., McCracken, L.A., Heimgartner, R., Fodor, I., Watrin, A., Seguin, P., Paoles, E., Van Den Keybus, K., Eberle, G., Schurch, B., Pralong, E., Becce, F., Prior, J., Buse, N., Buschman, R., Neufeld, E., Kuster, N., Carda, S., Zitzewitz, J.v., Delattre, V., Denison, T., Lambert, H., Minassian, K., Bloch, J. & Courtine, G. Targeted Neurotechnology Restores Walking in Humans with Spinal Cord Injury. Nature, 563(7729):65-93, 2018, doi:10.1038/s41586-018-0649-2
Yao, A., Zastrow, E. & Kuster, N. Data‐Driven Experimental Evaluation Method for the Safety Assessment of Implants With Respect to RF‐Induced Heating During MRI. Radio Science, 53(6):700-709, 2018, doi:10.1029/2017RS006433
Al-Serori, H., Kundi, M., Ferk, F., Misik, M., Nersesyan, A., Murbach, M., Lah, T.T. & Knasmüller, S. Evaluation of the potential of mobile phone specific electromagnetic fields (UMTS) to producemicronuclei in human glioblastoma cell lines. Toxicology in Vitro, 40:264-271, 2017
Corcoles, J., Zastrow, E. & Kuster, N. On the estimation of the worst-case implant-induced RF-heating in multi-channel MRI. Physics in Medicine & Biology, 62(12):4711-4727, 2017
Grossman, N., Bono, D., Dedic, N., Kodandaramaiah, S., Rudenko, A., Suk, H.J., Cassarà, A.M., Neufeld, E., Kuster, N., Tsai, L.H., Pascual-Leone, A. & Boyden, E. Noninvasive Deep Brain Stimulation via Delivery of Temporally Interfering Electric Fields. Cell, 169(6):1029—1041.e16, 2017
Kapri-Pardes, E., Hanoch, T., Maik-Rachline, G., Murbach, M., Bounds, P.L., Kuster, N. & Seger, R. Activation of signaling cascades by weak extremely low frequency electromagnetic fields. Cellular Physiology and Biochemistry, 43(4):1533-1546, 2017
Manser, M., Sater, M., Schmid, C., Noreen, F., Murbach, M., Kuster, N., Schuermann, D. & Schär, P. ELF‑MF Exposure Affects Robustness of Epigenetic Programming during Granulopoiesis. Scientific Reports, 7:43345, 2017
Moorselaar, I.v., Slottje, P., Heller, P., Strien, R.v., Kromhout, H., Murbach, M., Kuster, N., Vermeulen, R. & Huss, A. Effects of personalised exposure on self-rated electromagnetic hypersensitivity and sensibility - A double blind randomised controlled trial. Environment International, 99:255-262, 2017
Murbach, M., Neufeld, E., Samaras, T., Corcoles, J., Robb, F., Kainz, W. & Kuster, N. Pregnant Women Models Analyzed for RF Exposure and Temperature Increase within 3 T RF Shimmed Birdcages. Magnetic Resonance in Medicine, 77(5):2048-2056, 2017
Burckhardt, K., Szczerba, D., Neufeld, E., Muralidhar, K. & Kuster, N. Parallel Smoothing Pressure Correction Solver for Biomedical Flow Problems: Convergence Criteria, Preconditioning, Scalability. Progress in Computational Fluid Dynamics, 16(4):201-215, 2016
Datta, N.R., Krishnan, S., Speiser, D., Neufeld, E., Kuster, N., Bodis, S. & Hofmann, H. Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich's 'magic (nano)bullet' for cancer theranostics? Cancer Treatment Reviews, 50:217-227, 2016
Huss, A., Murbach, M., Moorselaar, I.v., Kuster, N., Strien, R.v., Kromhout, H., Vermeulen, R. & Slottje, P. Novel Exposure Units for at-Home Personalized Testing of Electromagnetic Sensibility. Bioelectromagnetics, 37(1):62-68, 2016
Murbach, M., Neufeld, E., Cabot, E., Zastrow, E., Corcoles, J., Kainz, W. & Kuster, N. Virtual Population-Based Assessment of the Impact of 3 Tesla Radiofrequency Shimming and Thermoregulation on Safety and B1+ Uniformity. Magnetic Resonance in Medicine, 76(3):986-997, 2016
Neufeld, E., Cassarà, A.M., Montanaro, H., Kuster, N. & Kainz, W. Functionalized Anatomical Models for EM-Neuron Interaction Modeling. Physics in Medicine & Biology, 61(12):4390-4401, 2016
Neufeld, E., Kyriacou, A., Kainz, W. & Kuster, N. Approach to validate simulation-based distribution predictions combining the Gamma-method and uncertainty assessment: application to focused ultrasound. Journal of Verification, Validation and Uncertainty Quantification, 1(3):031006-031006-8, 2016
Neufeld, E., Oikonomidis, I.V., Iacono, M., Angelone, L., Kainz, W. & Kuster, N. Investigation of Assumptions Underlying Current Safety Guidelines on EM-Induced Nerve Stimulation. Physics in Medicine & Biology, 61(12):4466-4478, 2016
Corcoles, J., Zastrow, E. & Kuster, N. Convex Optimization of MRI Exposure for Mitigation of RF-Heating from Active Medical Implants. Physics in Medicine & Biology, 60(18):7293-7308, 2015
Iacono, M., Neufeld, E., Akinnagbe, E., Wolf, J., Oikonomidis, I.V., Sharma, D., Wilm, B., Wyss, M., Prüssmann, K., Jakab, A., Makris, N., Cohen, E., Kuster, N., Kainz, W. & Angelone, L. MIDA: A Multimodal Imaging-Based Detailed Anatomical Model of the Human Head and Neck. PLoS ONE, 10(4):e0124126, 2015
Kyriakou, A., Neufeld, E., Werner, B., Szekely, G. & Kuster, N. Full-Wave Acoustic and Thermal Modeling of Transcranial Ultrasound Propagation and Investigation of Skull-Induced Aberration Correction Techniques: A Feasibility Study. Journal of Therapeutic Ultrasound, 3(11):1-18, 2015
Murbach, M., Zastrow, E., Neufeld, E., Cabot, E., Kainz, W. & Kuster, N. Heating and Safety Concerns of the Radio-Frequency Field in MRI. In Current Radiology ReportsCurrent Radiology Reports, 3(12), Springer, 2015, doi:10.1007/s40134-015-0128-6
Neufeld, E., Fütterer, M., Murbach, M. & Kuster, N. Rapid Method for Thermal Dose-Based Safety Supervision during MR Scans. Bioelectromagnetics, 36(5):398-407, 2015
Fedele, G., Edwards, M., Bhutani, S., Hares, J., Murbach, M., Green, E., Dissel, S., Hastings, M., Rosato, E. & Kyriacou, C. Genetic Analysis of Circadian Responses to Low Frequency Electromagnetic Fields in Drosophila Melanogaster. PLoS Genetics, 10(12):1-12, 2014
Gosselin, M.C., Neufeld, E., Moser, H., Huber, E., Farcito, S., Gerber, L., Jedensjoe, M., Hilber, I., Di Gennaro, F., Lloyd, B., Cherubini, E., Szczerba, D., Kainz, W. & Kuster, N. Development of a New Generation of High-Resolution Anatomical Models for Medical Device Evaluation: The Virtual Population 3.0. Physics in Medicine & Biology, 59(18):5287-5303, 2014
Hässig, M., Wullschleger, M., Naegeli, H., Kupper, J., Spiess, B., Kuster, N., Capstick, M. & Murbach, M. Influence of Non Ionizing Radiation of Base Stations on the Activity of Redox Proteins in Bovines. BMC Veterinary Research, 10(136):1-11, 2014, doi:10.1186/1746-6148-10-136
Murbach, M., Neufeld, E., Capstick, M., Kainz, W., Brunner, D., Samaras, T., Prüssmann, K. & Kuster, N. Thermal Tissue Damage Model Analyzed for Different Whole-Body SAR and Scan Durations for Standard MR Body Coils. Magnetic Resonance in Medicine, 71(1):421-431, 2014, doi:10.1002/mrm.24671
Murbach, M., Neufeld, E., Christopoulou, M., Achermann, P. & Kuster, N. Modeling of EEG Electrode Artifacts and Thermal Ripples in Human Radiofrequency Exposure Studies. Bioelectromagnetics, 35(4):273-283, 2014
Murbach, M., Neufeld, E., Kainz, W., Prüssmann, K. & Kuster, N. Whole Body and Local RF Absorption in Human Models as a Function of Anatomy and Position within 1.5T MR Body Coil. Magnetic Resonance in Medicine, 71(2):839-845, 2014, doi:10.1002/mrm.24690
Karampatzakis, A., Kühn, S., Tsanidis, G., Neufeld, E., Samaras, T. & Kuster, N. Antenna Design and Tissue Parameters Considerations for an Improved Modelling of Microwave Ablation in the Liver. Physics in Medicine & Biology, 58(10):3191-3206, 2013, doi:10.1088/0031-9155/58/10/3191
Karampatzakis, A., Kühn, S., Tsanidis, G., Neufeld, E., Samaras, T. & Kuster, N. Heating Characteristics of Antenna Arrays Used in Microwave Ablation: A Theoretical Parametric Study. IEEE Transactions on Biomedical Engineering, 43(10):1321-1327, 2013
Loughran, S., Benz, D., Schmid, M., Murbach, M., Kuster, N. & Achermann, P. No Increased Sensitivity in Brain Function of Children Exposed to Mobile Phone-Like Emissions. Clinical Neurophsyiology, 124(7):1303-1308, 2013, doi:10.1016/j.clinph.2013.01.010
Lustenberger, C., Murbach, M., Dürr, R., Schmid, M., Kuster, N., Achermann, P. & Huber, R. Stimulation of the Brain with Radiofrequency Electromagnetic Field Pulses Affects Sleep-Dependent Performance Improvement. Brain Stimulation, 6(5):805-811, 2013, doi:10.1016/j.brs.2013.01.017
Neufeld, E., Sczcerba, D., Chavannes, N. & Kuster, N. A Novel Medical Image Data-Based Multiphysics Simulation Platform for Computational Life Sciences. Interface Focus, 3(2):20120058, 2013, doi:10.1098/rsfs.2012.0058
Paulides, M., Stauffer, P., Neufeld, E., Maccarini, P., Kyriakou, A., Canters, R., Diederich, C., Bakker, J. & van Rhoon, G. Simulation Techniques in Hyperthermia Treatment Planning. International Journal of Hyperthermia, 29(4):346-357, 2013, doi:10.3109/02656736.2013.790092
van Rhoon, G., Samaras, T., Yarmolenko, P., Dewhirst, M., Neufeld, E. & Kuster, N. CEM43 Thermal Dose Thresholds: A Potential Guide for Magnetic Resonance Radiofrequency Exposure Levels? European Radiology, 23(8):2215-2227, 2013, doi:10.1007/s00330-013-2825-y
Waldmann, P., Bohnenberger, S., Greinert, R., Hermann-Then, B., Heselich, A., Klug, S., Koenig, J., Kuhr, K., Kuster, N., Merker, M., Murbach, M., Pollet, D., Schadenboeck, W., Scheidemann-Wesp, U., Schwab, B., Volkmer, B., Weyer, V. & Blettner, M. Influence of GSM Signals on Human Peripheral Lymphocytes: Study of Genotoxicity. Radiation Research, 179(4):243-253, 2013, doi:10.1667/RR2914.1
Xu, S., Chen, G., Chen, C., Sun, C., Zhang, D., Murbach, M., Kuster, N., Zeng, Q. & Xu, Z. Cell Type-Dependent Induction of DNA Damage by 1800 MHz Radiofrequency Electromagnetic Fields Does Not Result in Significant Cellular Dysfunctions. PLoS ONE, 8(1):e54906, 2013, doi:10.1371/journal.pone.0054906
Bakker, J., Paulides, M., Neufeld, E., Christ, A., Chen, X.L., Kuster, N. & van Rhoon, G. Children and Adults Exposed to Low Frequency Magnetic Fields at the ICNIRP Reference Levels: Theoretical Assessment of the Induced Electric Fields. Physics in Medicine & Biology, 57(7):1815-1829, 2012, doi:10.1088/0031-9155/57/7/1815
Kyriakou, A., Christ, A., Neufeld, E. & Kuster, N. Local Tissue Temperature Increase of a Generic Implant Compared to the Basic Restrictions Defined in Safety Guidelines. Bioelectromagnetics, 33(5):366-374, 2012, doi:10.1002/bem.21695
Kyriakou, A., Neufeld, E., Szczerba, D., Kainz, W., Lüchinger, R., Kozerke, S., McGregor, R. & Kuster, N. Patient Specific Simulations and Measurements of the Magneto-Hemodynamic Effect in Human Primary Vessels. Physiological Measurement, 33(2):117-130, 2012, doi:10.1088/0967-3334/33/2/117
Murbach, M., Christopoulou, M., Crespo-Valero, P., Achermann, P. & Kuster, N. Exposure System to Study Hypotheses of ELF and RF Electromagnetic Field Interactions of Mobile Phones with the Central Nervous System. Bioelectromagnetics, 33(6):527-533, 2012, doi:10.1002/bem.21710
Schmid, M., Loughran, S., Regel, S., Murbach, M., Grunauer, A.B., Rusterholz, T., Bersagliere, A., Kuster, N. & Achermann, P. Sleep EEG Alterations: Effects of Different Pulse-Modulated Radio Frequency Electromagnetic Fields. Journal of Sleep Research, 21(1):50-58, 2012, doi:10.1111/j.1365-2869.2011.00918.x
Schmid, M., Murbach, M., Lustenberger, C., Maire, M., Kuster, N., Achermann, P. & Loughran, S. Sleep EEG Alterations: Effects of Pulsed Magnetic Fields Versus Pulse-Modulated Radio Frequency Electromagnetic Fields. Journal of Sleep Research, 21(6):620-629, 2012, doi:10.1111/j.1365-2869.2012.01025.x
Bakker, J., Paulides, M., Neufeld, E., Christ, A., Kuster, N. & van Rhoon, G. Children and Adults Exposed to Electromagnetic Fields at the ICNIRP Reference Levels: Theoretical Assessment of the Induced Peak Temperature Increase. Physics in Medicine & Biology, 56(15):4967-4989, 2011, doi:10.1088/0031-9155/56/15/020
Murbach, M., Cabot, E., Neufeld, E., Gosselin, M.C., Christ, A., Prüssmann, K. & Kuster, N. Local SAR Enhancements in Anatomically Correct Children and Adult Models as a Function of Position Within 1.5 T MR Body Coil. Progress in Biophysics and Molecular Biology, 107(3):428-433, 2011, doi:10.1016/j.pbiomolbio.2011.09.017
Neufeld, E., Gosselin, M.C., Murbach, M., Christ, A., Cabot, E. & Kuster, N. Analysis of the Local Worst-Case SAR Exposure Caused by an MRI Multi-transmit Body Coil in Anatomical Models of the Human Body. Physics in Medicine & Biology, 56(15):4649-4659, 2011, doi:10.1088/0031-9155/56/15/002
Christ, A., Kainz, W., Hahn, E., Honegger, K., Zefferer, M., Neufeld, E., Rascher, W., Janka, R., Bautz, W., Chen, J., Kiefer, B., Schmitt, P., Hollenbach, H.P., Shen, J., Oberle, M., Szczerba, D., Kam, A., Guag, J. & Kuster, N. The Virtual Family - Development of Surface-Based Anatomical Models of Two Adults and Two Children for Dosimetric Simulations. Physics in Medicine & Biology, 55(2):N23-N38, 2010, doi:10.1088/0031-9155/55/2/N01
Kainz, W., Guag, J., Benkler, S., Szczerba, D., Neufeld, E., Krauthamer, V., Myklebust, J., Bassen, H., Chang, I., Chavannes, N., Kim, J.H., Sarntinoranont, M. & Kuster, N. Development and Validation of a Magneto-Hydrodynamic Solver for Blood Flow Analysis. Physics in Medicine & Biology: Special issue: The 4th Joint Symposium on Radiotherapy Research, 55(23):7253-7261, 2010, doi:10.1088/0031-9155/55/23/005
Paulides, M., Bakker, J., Linthorst, M., Zee, J.V.d., Rijnen, Z., Neufeld, E., Pattynama, P., Jansen, P., Levendag, P. & van Rhoon, G. The Clinical Feasibility of Deep Hyperthermia Treatment in the Head and Neck: New Challenges for Positioning and Temperature Measurement. Physics in Medicine & Biology, 55(9):2465-2480, 2010, doi:10.1088/0031-9155/55/9/003
Szczerba, D., Neufeld, E., Zefferer, M., Szekely, G. & Kuster, N. Unstructured Mesh Generation from the Virtual Family Models for Whole Body Biomedical Simulations. Procedia Computer Science, 1(1):837-844, 2010, doi:10.1016/j.procs.2010.04.091
Neufeld, E., Kühn, S., Szekely, G. & Kuster, N. Measurement, Simulation and Uncertainty Assessment of Implant Heating During MRI. Physics in Medicine & Biology, 54(13):4151-4169, 2009, doi:10.1088/0031-9155/54/13/012
Christ, A., Samaras, T., Neufeld, E., Klingenböck, A. & Kuster, N. SAR Distribution in Human Beings When Using Body-worn RF Transmitters. Radiation Protection Dosimetry, 124(1):6-14, 2007, doi:10.1093/rpd/ncm377
Neufeld, E. A New Planning Tool for Hyperthermic Cancer Treatment. ERCIM News(69)pages 31-32, 2007
Neufeld, E., Chavannes, N., Samaras, T. & Kuster, N. Novel Conformal Technique to Reduce Staircasing Artifacts at Material Boundaries for FDTD Modeling of the Bioheat Equation. Physics in Medicine & Biology, 52(15):4371-4381, 2007, doi:10.1088/0031-9155/52/15/001
Paulides, M., Bakker, J., Neufeld, E., Jansen, P., Levendag, P. & van Rhoon, G. The HYPERcollar: A Novel Applicator for Hyperthermia in the Head and Neck. International Journal of Hyperthermia, 23(8):567-576, 2007, doi:10.1080/02656730701670478

Latest News