MRI exposure of the Virtual Population: MRIxViP

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The development of high resolution anatomical phantoms has enabled the comprehensive analysis of populations, in approaches such as in silico clinical trials. However, such analyses are computationally expensive, particularly for cases where the results must be verified and validated.

IT'IS has precomputed two standard libraries of RF-induced electromagnetic fields (EMF) distributions inside the human body, resulting from exposure to a representative set of radiofrequency (RF) birdcage coils used for 1.5T (MRIxViP1.5T) and 3T (MRIxViP3.0T) closed-bore commercial MRI scanners. Each library consists of induced-field data from all relevant landmark positions simulated our popular Virtual Population (ViP) phantoms in the supine posture in 20 birdcage coils – for a total of more than 10,000 clinical scanning scenarios.

Together with the IMAnalytics module by ZMT Zurich MedTech AG, MRIxViP enables users to perform ISO 10974 Tier 2 and 3 evaluations of implants with full data traceability. The complete toolchain, IMAnalytics with MRIxViP, is qualified by the US FDA for assessment of implant RF compatibility with MR examinations per ISO 10974 or ASTM F2182 as a Medical Device Development Tool (MDDT).



VIP BMI tgSpecifications of MRIxViP V2.1

  • 20,424 3D electric and magnetic field distributions at a resolution finer than 2x2x2 mm
  • 20 birdcage coils (10 for 1.5T and 10 for 3.0T, respectively) of different dimensions derived from a survey of existing 1.5T and 3.0T closed-bore commercial scanners
  • Twelve different adult and pediatric ViP phantom models in the supine posture (Duke, Ella, Billie, Thelonious, Fats, Glenn, Louis, Eartha, Yoon-sun, and morphed variants of Ella and Fats)
  • Head-to-foot imaging landmarks of the ViP models inside the RF coils, at 5 cm and 2.5 cm imaging steps for 1.5T and 3.0T, respectively