EXPOSURE LIBRARIES
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OVERVIEW

MRI exposure of the Virtual Population: MRIxViP

210326 MRIxViP timeline s2

 

 

The development of high resolution anatomical phantoms has enabled the comprehensive analysis of populations, in approaches such as in silico clinical trials. However, such analyses are computationally expensive, particularly for cases where the results must be verified and validated.

IT'IS has precomputed two standard libraries of RF-induced electromagnetic fields (EMF) distributions inside the human body, resulting from exposure to a representative set of radiofrequency (RF) birdcage coils used for 1.5T (MRIxViP1.5T) and 3T (MRIxViP3.0T) closed-bore commercial MRI scanners. Each library consists of induced-field data from all relevant landmark positions simulated our popular Virtual Population (ViP) phantoms in the supine posture in 20 birdcage coils – for a total of more than 12,000 clinical scanning scenarios.

Together with the IMAnalytics module by ZMT Zurich MedTech AG, MRIxViP enables users to perform ISO 10974 Tier 2 and 3 evaluations of implants with full data traceability. The complete toolchain, IMAnalytics with MRIxViP, is qualified by the US FDA for assessment of implant RF compatibility with MR examinations per ISO 10974 or ASTM F2182 as a Medical Device Development Tool (MDDT).

 

 

Specifications of MRIxViP V2.2

  • 24,124 3D electric and magnetic field distributions at a resolution finer than 2x2x2 mm
  • 20 birdcage coils (10 for 1.5T and 10 for 3.0T, respectively) of different dimensions derived from a survey of existing 1.5T and 3.0T closed-bore commercial scanners
  • Fourteen different adult and pediatric ViP phantom models in the supine posture (Duke, Ella, Billie, Thelonious, Fats, Glenn, Louis, Eartha, Yoon-sun, Jeduk, Eddie, and morphed variants of Ella and Fats)
  • Head-to-foot imaging landmarks of the ViP models inside the RF coils, at 5 cm and 2.5 cm imaging steps for 1.5T and 3.0T, respectively 
  Landmark Position (mm) where 0 is between the eyes and the ears
ViP Model  Top of Head

C1 Vertebra

T1 Vertebra L1 Vertebra

Bottom of Coccyx

Bottom of Feet

Billie -115 35 129 378 601 1410
Duke -89 82 209 524 806 1705
Eartha -112 46 123 343 528 1275
Eddie -108 57 182 499 800 1757
Ella -121 41 148 427 687 1527
Fats -104 64 192 501 781 1744
Glenn -78 85 204 503 758 1695
Jeduk -126 48 177 486 768 1500
Louis -91 69 175 438 694 1635
Thelonious -114 32 106 290 471 1045
YoonSun -113 39 141 392 635 1547