Estimated All-Day and Evening Whole-Brain Radiofrequency Electromagnetic Fields Doses, and Sleep in Preadolescents

Alba Cabré-Riera, Luuk van Wel, Ilaria Liorni, M. Elisabeth Koopman-Verhoeff, Liher Imaz, Jesús Ibarluzea, Anke Huss, Joe Wiart, Roel Vermeulen, Wout Joseph, Myles Capstick, Martine Vrijheid, Elisabeth Cardis, Martin Röösli, Marloes Eeftens, Arno Thielens, Henning Tiemeier, Mònica Guxens, Environmental Research 2021, 112291, online 29 October 2021; doi: 10.1016/j.envres.2021.112291

Radio-Frequency Exposure of the Yellow Fever Mosquito (A. aegypti) from 2 to 240 GHz

Eline De Borre, Wout Joseph, Reza Aminzadeh, Pie Müller, Matthieu Boone, Iván Josipovic, Sina Hashemizadeh, Niels Kuster, Sven Kühn, and Arno Thielens, PLOS Computational Biology 2021, Volume 17, Issue 10, Article Number e1009460, online 28 October 2021; doi: 10.1371/journal.pcbi.1009460

On the Dielectric Measurement of Thin Layers Using Open-Ended Coaxial Probes

Arya Fallahi, Sina Hashemizadeh, and Niels Kuster, IEEE Transactions on Instrumentation and Measurement, Volume 70, Article number: 3123257, online 26 October 2021; doi: 10.1109/TIM.2021.3123257

Young Investigator Best Abstract Award at ICHO2021

The Young Investigator Best Abstract Award at ICHO2021 was given to IT'IS PhD student Redi Poni.

ESHO Benchmarks for Computational Modeling and Optimization in Hyperthermia Therapy

Margarethus M. Paulides, Dario B. Rodrigues, Gennaro G. Bellizzi, Kemal Sumser, Sergio Curto, Esra Neufeld, Hazael Montanaro, H. Petra Kok, and Hana Dobsicek Trefna, International Journal of Hyperthermia 2021, Volume 38, Issue 1, pp. 1425–1442, online 28 September 2021; doi:10.1080/02656736.2021.1979254

Student Platform Award at BioEM2021

IT'IS PhD student Redi Poni was awarded a student platform award for excellence in his online presentation at BioEM2021

Temperature Dependence of the Microwave Dielectric Properties of γ‑Aminobutyric Acid

Jie Hou, Sisay Mebre Abie, Runar Strand-Amundsen, Yuri M. Galperin, Joakim Bergli, Christin Schuelke, Sina Hashemizadeh, and Ørjan Grøttem Martinsen, Scientific Reports 2021, Volume 11, Article Number 18082, online 10 September 2021; doi: 10.1038/s41598-021-97178-7

MorphoSONIC: A Morphologically Structured Intramembrane Cavitation Model Reveals Fiber-Specific Neuromodulation by Ultrasound

Théo Lemaire, Elena Vicari, Esra Neufeld, Niels Kuster, and Silvestro Micera, iScience, September 2021, Volume 24, Issue 9, Article No. 103085, online 6 September 2021; doi: https://doi.org/10.1016/j.isci.2021.103085

IT’IS Receives o²S²PARC Year 5 Award

IT’IS has entered its fifth year of support for establishing a unique modeling and simulation platform within the SPARC program

Induced Radiofrequency Fields in Patients Undergoing MR Examinations: Insights for Risk Assessment

Aiping Yao, Manuel Murbach, Tolga Goren, Earl Zastrow, Wolfgang Kainz, and Niels Kuster, Physics in Medicine and Biology, Volume 66, Article Number 185014, September 2021, online 26 August 2021; doi: 10.1088/1361-6560/ac212d

Transverse Confinement of Electron Beams in a 2D Optical Lattice for Compact Coherent X-Ray Sources

Arya Fallahi, Niels Kuster, and Lukas Novotny, New Journal of Physics, 23 August 2021, Volume 23, Article number: 083033, online 04 August 2021; https://doi.org/10.1088/1367-2630/ac1a99

Reflection Properties of the Human Skin From 40 to 110 GHz: A Confirmation Study

Andreas Christ, Adrian Aeschbacher, Fereshteh Rouholahnejad, Theodoros Samaras, Bernadetta Tarigan, and Niels Kuster, Bioelectromagnetics, Volume 42, No. 7, pp. 562 – 574, October 2021, online 21 July 2021; doi: 10.1002/bem.22362

Feasibility of Temperature Control by Electrical Impedance Tomography in Hyperthermia

Redi Poni, Esra Neufeld, Myles Capstick, Stephan Bodis, Theodoros Samaras, and Niels Kuster, Cancers, Volume 13, Issue 13, Article No. 3297, online 30 June 2021; doi: 10.3390/cancers13133297

The SPARC DRC: Building a Resource for the Autonomic Nervous System Community

Mahyar Osanlouy, Anita Bandrowski, Bernard De Bono, David Brooks, Antonino M. Cassarà, Richard Christie, Nazanin Ebrahimi, Tom Gillespie, Jeffrey S. Grethe, Leonardo A. Guercio, Maci Heal, Mabelle Lin, Niels Kuster, Maryann E. Martone, Esra Neufeld, David Phillip Nickerson, Elias G. Soltani, Susan J. Tappan, Joost B. Wagenaar, Katie Zhuang, and Peter Hunter, Frontiers in Physiology 2021, Volume 12, 929, online 24 June 2021; https://doi.org/10.3389/fphys.2021.693735

Compliance Assessment of the Epithelial or Absorbed Power Density Below 10 GHz Using SAR Measurement Systems

Theodoros Samaras, Andreas Christ, and Niels Kuster, Bioelectromagnetics, September 2021, Volume 42, Issue 6, Pages 484–490, online 15 June 2021; https://doi.org/10.1002/bem.22355

In Silico Voltage-Sensitive Dye Imaging Reveals the Emergent Dynamics of Cortical Populations

Taylor H. Newton, Michael W. Reimann, Marwan Abdellah, Grigori Chevtchenko, Eilif B. Muller, and Henry Markram , Nature Communications 2021, Volume 12, 3630, online 15 June 2021; doi: https://doi.org/10.1038/s41467-021-23901-7

Radiofrequency-Induced Heating of Broken and Abandoned Implant Leads During Magnetic Resonance Examinations

Aiping Yao, Tolga Goren, Theodoros Samaras, Niels Kuster, and Wolfgang Kainz, Magnetic Resonance in Medicine, October 2021, Volume 86, Issue 4, Pages 2156–2164, online 03 June 2021; doi: 10.1002/mrm.28836

FDA Extends MDDT Qualification to IMAnalytics V3.0 and MRIxViP V2.1

FDA Qualification of the IT’IS & ZMT MDDT toolset IMAnalytics with MRIxViP1.5T/3.0T and BCLib now also includes passive implants (ASTM F2182-19^ε2) and Region-of-Interest Field Extraction for ISO 10974 Tier 2.

The Impact of CT Image Parameters and Skull Heterogeneity Modeling on the Accuracy of Transcranial Focused Ultrasound Simulations

Hazael Montanaro, Cristina Pasquinelli, Hyunjoo J. Lee, Hyunggug Kim, Hartwig R. Siebner, Niels Kuster, Axel Thielscher, and Esra Neufeld, Journal of Neural Engineering 2021, Volume 18, Issue 4, Article number: 046041, online 04 May 2021; doi: 10.1088/1741-2552/abf68d

Computational and Phantom-Based Feasibility Study of 3D dcNCI with Ultra-Low Field MRI

Nora Höfner, Jan-Hendrik Storm, Peter Hömmen, Antonino M. Cassarà, and Rainer Körber, Frontiers in Physics 2021, Volume 9, Article number: 647376, online 26 April 2021; doi: 10.3389/fphy.2021.647376

IT'IS Annual Report 2020

Experimental and Numerical Optimization Modelling to Reduce Radiofrequency-Induced Risks of Magnetic Resonance Examinations on Leaded Implants

Juan Córcoles, Aiping Yao, and Niels Kuster, Applied Mathematical Modelling, August 2021, Volume 96, pages 177–188, online 09 March 2021; doi: 10.1016/j.apm.2021.02.036

MRI Mice V1.0: New Mouse Models for Computational Investigations

IT’IS has released four new mouse models segmented from magnetic resonance imaging data. All four models – a pregnant model, a 12-week-old female and male model and a 3-week-old male model – are posable and are made available together with the corresponding MR images.

Radio-Frequency Electromagnetic Field Exposure and Contribution of Sources in the General Population: An Organ-Specific Integrative Exposure Assessment

Luuk van Wel, Ilaria Liorni, Anke Huss, Arno Thielens, Joe Wiart, Wout Joseph, Martin Röösli, Milena Foerster, Amelie Massardier-Pilonchery, Myles Capstick, Elisabeth Cardis, and Roel Vermeulen, Journal of Exposure Science & Environmental Epidemiology 2021, online 02 March 2021; doi: 10.1038/s41370-021-00287-8

Towards Blood Flow in the Virtual Human: Efficient Self-Coupling of HemeLB

J. W. S. McCullough, R. A. Richardson, A. Patronis, R. Halver, R. Marshall, M. Ruefenacht, B. J. N. Wylie, T. Odaker, M. Wiedemann, B. Lloyd, E. Neufeld, G. Sutmann, A. Skjellum, D. Kranzlmüller, and P. V. Coveney, Interface Focus, February 2021, Volume 11, 20190119, online 11 December 2020, doi: https://doi.org/10.1098/rsfs.2019.0122

NeuroRat V4-0 – Detailed Rat Anatomy for Neuromodulation Investigations

It’s a rat! After two long years of unremitting work, IT’IS has released NeuroRat V4-0, the first computational anatomical model with nerve trajectories for neuro-electrophysiology simulations. The new posable and functionalized whole-body model includes 179 tissues and functionalized nerve trajectories.

A Calibrated Physical Flow Standard for Medical Perfusion Imaging

Gertjan Kok, Nikola Pelevic, Amedeo Chiribiri, Xenios Milidonis, Muhummad Nazir, Myles Capstick, Sita Drost, Christian Poelma, Tobias Schaeffter, Flow Measurement and Instrumentation, April 2021, Volume 78, Article number: 101907, online 02 February 2021; doi: 10.1016/j.flowmeasinst.2021.101907

Restoration of Breathing after Opioid Overdose and Spinal Cord Injury Using Temporal Interference Stimulation

Michael D. Sunshine, Antonino M. Cassarà, Esra Neufeld, Nir Grossman, Thomas H. Mareci, Kevin J. Otto, Edward S. Boyden, and David D. Fuller, Communications Biology 2021, Volume 4, Article number 107, online 25 January 2021; doi: https://doi.org/10.1038/s42003-020-01604-x

MARTIN V1.0 and ViP Hand Library for WPT Evaluations

As of this week, a new whole body pediatric numerical simulation model of a 29-month-old boy is available in our extended Virtual Population (ViP) library. MARTIN V1.0 was developed by the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital, Boston, USA, and will be hosted by IT’IS. We are also pleased to announce the release of the IT’IS ViP Hand Library specifically designed for evaluation of wireless power transfer systems. 

Non-Invasive Suppression of Essential Tremor Via Phase-Locked Disruption of its Temporal Coherence

Sebastian R. Schreglmann, David Wang, Robert L. Peach, Junheng Li, Xu Zhang, Anna Latorre, Edward Rhodes, Emanuele Panella, Antonino M. Cassara, Edward S. Boyden, Mauricio Barahona, Sabato Santaniello, John Rothwell, Kailash P. Bhatia, and Nir Grossman, Nature Communications, January 2021, Volume 12, Article number: 363, online 13 January 2021; doi: 10.1038/s41467-020-20581-7