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Numerical Modeling for Safety Assessment of Neurostimulation in Proximity of Medical Implants exposed to Low-Frequency Electromagnetic Fields (PhD)

Numerical Modeling for Safety Assessment of Neurostimulation in Proximity of Medical Implants Exposed to Low-Frequency Electromagnetic Fields (PhD)

Workplace:
Zurich, Switzerland
Company:
IT'IS Foundation for Research on Information Technologies in Society,
ETH (Swiss Federal Institute of Technology) Zurich
Description:

The IT'IS Foundation is an independent non-profit research organization dedicated to improving and advancing the quality of people’s lives through enhancing the safety and quality of emerging electromagnetic (EM) technologies. The Foundation’s primary activities include computational EM in complex environments, computational life sciences (CLS) applied to devices in and around the human body, and the development of high-resolution computable whole-body anatomical models derived from medical imaging data.

We are seeking a PhD candidate in numerical modeling to investigate the risk of neurostimulation in proximity of passive/active implants exposed to EM fields in the low-frequency (LF) domain generated by, e.g., wireless power transfer (WPT) systems and magnetic resonance imaging (MRI) gradients. The project involves a careful analysis of the underlying mechanisms of neurostimulation for different exposure conditions, and the identification of computational approaches for its quantification. Specifically, the focus will be on (i) the development and use of coupled EM and neuronal simulations; (ii) the development of electrical models of implant electrodes and electrophysiological realistic nerves/axons; (iii) the use of EM solvers to assess LF exposure conditions in proximity of implants; (iv) a systematic investigations of different characteristics of LF exposure, electrode geometries, axonal trajectories, nerve models and parameters affecting neurostimulation; and (v) the development of computational approaches for the identification of worst-case scenarios for neurostimulation in proximity of active/passive implants.

Education:
  • MSc degree in electrical engineering, biomedical engineering, or physics
  • Interest in and basic knowledge of
    • bioelectromagnetism
    • numerical simulations of EM fields
    • neurostimulation and computational neuroscience
    • biomedical engineering
    • exposure assessment and antenna design
  • Good knowledge of MATLAB and Python
  • Experience with the NEURON framework a plus
  • Experience programming in C++ a plus
  • Excellent command of the English language
  • Reliability, self-motivation, good organizational skills, and ability to cope with irregular and heavy workloads
  • Excellent ability to work both independently and as part of a team
Beginning:
As soon as possible.
Application Process:  

Applications should consist of:

  • Cover letter, including the position title and a statement elaborating on the applicant's fitness for the position and motivation to apply
  • Detailed CV, 2 pages maximum
  • Copies of diplomas and / or degree certificates, including grades
  • Letters of recommendation

For further information or to discuss the scope of this position, please contact Dr. Antonino M. Cassarà (cassara@itis.swiss or phone +41 44 245 9683).

Contact address:

We look forward to receiving your complete resume materials as a single pdf file at: hr@z43.swiss.

Dr. Mimi Sun
IT'IS Foundation
Zeughausstrasse 43
CH-8004 Zurich
Switzerland