Jan 1, 2019 - Dec 31, 2022


Logo neuHeartNeuHeart – A neuroprosthesis to Restore the Vagal-Cardiac Closed-Loop Connection after Heart Transplantation

IT’IS is pleased to announce the award of the project NeuHeart – "A neuroprosthesis to restore the vagal-cardiac closed-loop connection after heart transplantation." The project is funded by the European Union (EU) in response to the Horizon 2020 FET proactive call in support of emerging technologies.

Horizon 2020 is the EU's Research and Innovation program for funding projects to support European competitiveness. The NeuHeart project is funded via the "Future and Emerging Technologies" (FET) call for "Research and Innovation Actions" for high-risk forward looking research to prosper in Europe, and FET Innovation Launchpad Actions aiming at turning results from FET-funded projects into genuine societal or economic innovations.

A heart transplant can significantly increase the life expectancy of patients affected by end-stage heart failure. Transplant recipients suffer, however, from late complications related to cardiac denervation. The main goal of NeuHeart is to address this fundamental clinical problem through a bioelectronic solution for neuromodulation of the vagus nerve (VN). A cardiac smart neuroprosthesis will be developed to provide a regenerative neural interface for VN stimulation with implanted artificial sensors for recording sensory information. The project's outcomes will contribute to the fundamental research of heart transplant science with the promise of a new treatment paradigm for treatment of heart failure.

The NeuHeart project consortium is led by the Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna (Italy); other participants in addition to IT'IS are University College London (United Kingdom), the Medical University of Vienna (Austria), the Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (Germany), and SensArs Neuroprosthetics Sàrl (Switzerland).