The new models “mViP” became possible thanks to our recent important achievements to extend non-linear large deformation constitutive equations with a tissue growth term, as well as a robust approach to adaptive unstructured mesh generation that allow to combine morphing with interactive posture editing running on a desktop computer. In the new morphed models, the subcutaneous adipose tissue (SAT) is morphed to simulate how an individual would gain (or lose) weight. The SAT volume expansion, analogous to thermal expansion, deforms surrounding tissue elastically while being constrained by rigid bones.
Three different morphed versions of Ella (22, 26, 30 kg/m²) and Fats (29, 33, 40 kg/m²) have been released at this point, closing major gaps in terms of BMI distribution across our Virtual Population. In addition, a modified model of Ella (Ella Breast Coil) that has been created for specific applications, such as breast coil design or safety assessments, is provided.
Additional morphed models that cover higher BMI values or that take other tissues (e.g., muscle tissue) into consideration will become available soon. Based on the new technology, we are able to provide customized models for specific applications on demand (firstname.lastname@example.org).