National Toxicology Program (NTP) Technical Reports TR595 and TR596
The two final technical reports (TR) of the National Toxicology Program (NTP) rodent studies are now available. The conclusions reported in the TRs – entitled "Toxicology and Carcinogenesis Studies in Hsd:Sprague Dawley SD Rats Exposed to Whole-Body Radio Frequency Radiation at a Frequency (900 MHz) and Modulations (GSM and CDMA) Used by Cell Phones" (TR595) and "Toxicology and Carcinogenesis Studies in B6C3F1/N Mice Exposed to Whole-Body Radio Frequency Radiation at a Frequency (1,900 MHz) and Modulations (GSM and CDMA) Used by Cell Phones” (TR596) – are in line with the draft reports released in February, with "some evidence" for a link to cancer upgraded to "clear evidence" on the basis of the March 2018 peer review of the draft reports. The release of these reports has been covered widely in the press.
The scientific and technical impact of the report on rats can be summarized as:
- Clear evidence was found in male rats for a link between exposure and the incidence of malignant schwannomas in the heart
- Some evidence was found in male rats for malignant gliomas in the brain
- Equivocal evidence was found in male rats for the incidence of tumors in the adrenal medulla and in female rats for the incidence of malignant schwannomas in the heart
- The survival of all exposed groups of male rats was significantly greater than that of controls
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The scientific and technical impact of the report on mice can be summarized as:
- Equivocal evidence was found in male mice the incidence of fibrosarcoma, sarcoma, or malignant fibrous histiocytoma in the skin and alveolar/ bronchiolar adenoma or carcinoma in the lung
- Equivocal evidence was found in female mice for the incidence of malignant lymphoma (all organs)
- The survival of male mice exposed at 5 W/kg (GSM) or 2.5 W/kg (CDMA) was significantly greater than that of controls but not for the other exposure levels
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