In an entirely patient-based approach, a feasibility study was undertaken to assess the use of low energy emission therapy in the treatment of cancer. The study demonstrated that cancer-related EM frequencies are tumor specific and that the treatment of patients with the specific frequency is feasible, well tolerated and may have biological efficacy in patients with advanced cancer. The next important step is to clarify the underlying mechanisms. SPEAG developed the RF system and the IT'IS Foundation provided expert advice on the exposure schemes and dosimetric analysis.