Jan 15, 2008
Study on Potential Effects of '902-MHz GSM-type Wireless Communication Signals' on DBMA-induced Mammary Tumours in Sprague-Dawley Rats
Robert Hruby, Georg Neubauer, Niels Kuster and Michael Frauscher, in Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 649, Issue 1-2, pp. 34–44, January 2008
This study was the second co-carcinogenic confirmation study utilizing the DMBA-induced mammary tumor model (Yu et al (2006)). Five groups of 100 Sprague-Dawley rats were exposed to 902-MHz GSM-type Signals (4 ,1.33, 0.46 W/kg, sham and control) after orally administering DMBA. Statistically significant differences between RF-exposed groups and the sham-exposed group were that all RF-exposed groups had, at various times, significantly more palpable tissue masses. There were fewer animals with benign neoplasms, but more with malignant tumours in the high-dose group. In addition, there were more adenocarcinomas in the low-dose group, more malignant neoplasms in the low- and high-dose groups, more animals with adenocarcinomas in the high-dose group, and fewer animals with fibroadenomas in the low- and mid-dose groups. The cage-control group had, when compared with the sham-exposed group, statistically significantly more palpable tissue masses, more benign and also more malignant neoplasms. The cage-control group had in most aspects the highest incidence and malignancy of neoplasms among all groups. No clear conclusions could be drawn from these findings.
