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27/09/2006

Development of Novel Whole-Body Exposure Setups for Rats Providing High Efficiency, National Toxicology Program (NTP) Compatibility and Well-Characterized Exposure

Wolfgang Kainz, Neviana Nikoloski, Walter Oesch, Veronica Berdiñas-Torres, Jürg Fröhlich, Georg Neubauer, and Niels Kuster, in Physics in Medicine and Biology, Volume 51, Number 20, pp. 5211–5229, October 2006. Published online 27 Sept 2006


This paper presents the design, optimization, realization and verification of novel whole-body exposure setups for rats. The setups operating at 902 MHz and 1747 MHz provide highly efficient, National Toxicology Program (NTP) compatible and well-characterized exposures. They are compared to existing concepts of exposure setups with respect to efficiency, induced field uniformity, good laboratory practice (GLP) compatibility and cost. The described exposure facility was one of the corner stones of PERFORM A.

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