Response, Thermal Regulatory Threshold and Thermal Breakdown Threshold of Restrained RF-Exposed Mice at 905 MHz

Sven Ebert, Sang-Jin Eom, Jürgen Schuderer, U. Apostel, Thomas Tillmann, Clemens Dasenbrock and Niels Kuster, in Physics in Medicine & Biology, Volume 50, Number 21, pp. 5203–5215, October 2005

The objective of this study was the determination of the thermal regulatory and the thermal breakdown thresholds for in-tube restrained B6C3F1 and NMRI mice exposed to radiofrequency electromagnetic fields at 905 MHz. Different levels of the whole-body averaged specific absorption rate (SAR = 0, 2, 5, 7.2, 10, 12.6 and 20 W kg-1) have been applied at 22 ± 2 °C and 30-70% humidity. The thermal regulatory threshold was found at SAR levels between 2 W kg-1 and 5 W kg-1, whereas the breakdown of regulation was determined at 10.1 ± 4.0 W kg-1(K = 2) for B6C3F1 mice and 7.7 ± 1.6 W kg-1(K = 2) for NMRI mice, A dependence upon the metabolic rate and weight could be shown. The presented data suggest that the thermal breakdown for in-tube restrained mice can occur at SAR levels of 6 W kg-1 at laboratory conditions.

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