Apr 1, 2005

Reevaluation and Improved Design of the TEM Cell In Vitro Exposure Unit for Replication Studies

Neviana Nikoloski, Jürg Fröhlich, Theodoros Samaras, Jürgen Schuderer and Niels Kuster, Bioelectromagnetics Vol. 26, Issue 3, pp. 215–224, April 2005

The transverse electromagnetic (TEM) cell system developed by T. Litovitz, D. Krause, L.M. Penafiel, E. Elson, and J.M. Mullins (1993); and utilized by L.M. Penafiel, T. Litovitz, D. Krause, A. Desta, and J.M. Mullins (1997) for the exposure of cells in T25 flasks at 835 MHz has been reevaluated and a greatly improved setup has been constructed. At 835 MHz, the average SAR within the medium is 6.0 W/kg at 1W input power with a standard deviation of less than 52%. The temperature increase was reduced to 0.045 °C/(W/kg) by applying active air flow cooling. These results do not correspond to the previous study reporting an average SAR within the medium of 2.5 W/kg at an input power of 0.96W.

Due to the large interest, the IT'IS Foundation offers copies of this setup. The setup allows well defined exposure from a few MHz up to 1GHz.